Troponin T Cardiac High Sensitivity
Ordering Info & Methodology
Test Code
Cerner Synonyms
CTROPT
TnT, Troponin T, Troponin T
Turn Around Time
Methodology
Analyzed within 1 day of receipt.
Sandwich immunoassay, electrochemiluminescence, Roche Cobas
Ordering Guide
Specimen Requirements
Sample Type
Collection Container
Alternate Collection Containers
Lithium Heparin Plasma
Light Green
Gold, Red
1.0 mL
24 hours
Add on stability
This is the length of time after sample collection that this analyte is stable. Test can be added to a previously collected sample if the time since collection is less than the add on stability time.
Minimum Volume
Add On Stability
Collection and Shipping Requirements
Refrigerate. Send on ice pack.
Reference Intervals
Female Reference Interval
Age Category | Reference Interval | units |
|---|---|---|
≥ 12 m | <9 | ng/L |
Male Reference Interval
Age Category | Reference Interval | units |
|---|---|---|
≥ 12 m | <14 | ng/L |
Additional Notes
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Measurement Uncertainty (MU)
Every laboratory value is an estimate of the true concentration of substance. MU is the 95% confidence interval around that estimate. 95% of the time, the true concentration will be within the range of the reported value ±MU. This value is based on analytical variability (precision) and does not reflect other factors such as sample collection and handling which may also affect the result.
Example
Reported sodium = 140 mmol/L
Sodium MU = 1%
Expanded uncertainty = 140 mmol/L ± 1% or 140mmol/L ± 1.4 mmol/L
Interpretation - the true value of sodium in the sample is in the range 138.6-141.4 mmol/L, with 95% confidence.
9%
Measurement Uncertainty
The clinical utility of a single troponin value to rule in or rule out acute myocardial infarction is limited except in the setting of acute chest pain which has been ongoing >3 hours. Generally, the measurement of a baseline and a 3 hour troponin is advised.
At 3 hours post baseline, a delta hsTnT of <5 ng/L is a sensitive indicator to assist in ruling-out a NSTEMI, while a delta hsTnT of ≥ 20 ng/L is a specific indicator for ruling-in acute myocardial damage.
Intermediate delta hsTnT values neither rule-in nor rule-out an acute MI, and must be interpreted in conjunction with the pretest probability of disease, or with a subsequent delta hsTnT.
In patients with renal failure and elevated baseline hsTnT, a delta hsTnT of <10% is a sensitive indicator to assist in ruling-out a NSTEMI, while a delta hsTnT of ≥ 30% is a specific indicator for ruling-in acute myocardial damage, assuming that the patient's renal function is in a steady state.
Assay interferences are possible in patients taking high dose (>5mg/day) biotin supplementation.