Adrenocorticotropic Hormone (ACTH)
Ordering Info & Methodology
Test Code
Cerner Synonyms
ACTH
ACTH Level, ACTH, Adrenocorticotropic Hormone, Corticotropin, Adrenal Corticotropin Hormone
Turn Around Time
Methodology
Analyzed within 4 days of receipt.
Sandwich immunoassay, electrochemiluminescence, Roche Cobas
Ordering Guide
ACTH. For petrosal sinus sampling, order ACTHPS battery.
Specimen Requirements
Sample Type
Collection Container
Alternate Collection Containers
EDTA Plasma
Lavender
1.0 mL
Cannot be added on to previously collected sample.
Add on stability
This is the length of time after sample collection that this analyte is stable. Test can be added to a previously collected sample if the time since collection is less than the add on stability time.
Minimum Volume
Add On Stability
Collection and Shipping Requirements
Centrifuge at 4°C, freeze. Send frozen on dry ice. Must arrive at SPH frozen. Thawed specimens will be rejected.
Reference Intervals
Female Reference Interval
Age Category | Reference Interval | units |
|---|---|---|
≥ 0y | <14 | pmol/L |
Male Reference Interval
Age Category | Reference Interval | units |
|---|---|---|
≥ 0y | <14 | pmol/L |
Additional Notes
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Measurement Uncertainty (MU)
Every laboratory value is an estimate of the true concentration of substance. MU is the 95% confidence interval around that estimate. 95% of the time, the true concentration will be within the range of the reported value ±MU. This value is based on analytical variability (precision) and does not reflect other factors such as sample collection and handling which may also affect the result.
Example
Reported sodium = 140 mmol/L
Sodium MU = 1%
Expanded uncertainty = 140 mmol/L ± 1% or 140mmol/L ± 1.4 mmol/L
Interpretation - the true value of sodium in the sample is in the range 138.6-141.4 mmol/L, with 95% confidence.
5%
Measurement Uncertainty
Reference interval applies to specimens collected between 7 and 10 AM, or within the first 3 hours of waking. Assay interference is possible in the presence of elevated quantities of ACTH fragments, precursors and synthetic analogues. Assay interferences are possible in patients taking high dose (>5mg/day) biotin supplementation.