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C-Reactive Protein High Sensitivity

Ordering Info & Methodology

Test Code

Cerner Synonyms

CRPB

CRP High Sensitivity, C Reactive Protein, C Reactive Protein (CRP), CRP (C-Reactive Protein), CRP, C-Reactive, hsCRP

Turn Around Time

Methodology

Analyzed within 4 hours of receipt, 24/7. Available on a STAT basis.

Immunoturbidimetric, Roche cobas c

Ordering Guide

If ordered together with ESR, only CRP will be performed.

Specimen Requirements

Sample Type

Collection Container

Alternate Collection Containers

Lithium Heparin Plasma

Light Green

Gold, Red

1.0 mL

Seven days

Add on stability
This is the length of time after sample collection that this analyte is stable. Test can be added to a previously collected sample if the time since collection is less than the add on stability time.

Minimum Volume

Add On Stability

Collection and Shipping Requirements

Refrigerate. Send on ice pack within 3 days of collection or frozen if longer.

Reference Intervals

Female Reference Interval

Age Category
Reference Interval
units
0 y - <2 d
Not Established
mg/L
< 15 d
< 6.1
mg/L
15 d - <19 y
< 2.1
mg/L
≥ 20 y
< 3.1
mg/L

Male Reference Interval

Age Category
Reference Interval
units
0 y - <2 d
Not Established
mg/L
< 15 d
< 6.1
mg/L
15 d - <19 y
< 2.1
mg/L
≥ 20 y
< 3.1
mg/L
Additional Notes

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Measurement Uncertainty (MU)
Every laboratory value is an estimate of the true concentration of substance. MU is the 95% confidence interval around that estimate. 95% of the time, the true concentration will be within the range of the reported value ±MU. This value is based on analytical variability (precision) and does not reflect other factors such as sample collection and handling which may also affect the result.

Example

Reported sodium = 140 mmol/L
Sodium MU = 1%
Expanded uncertainty = 140 mmol/L ± 1% or 140mmol/L ± 1.4 mmol/L
Interpretation - the true value of sodium in the sample is in the range 138.6-141.4 mmol/L, with 95% confidence.

4%

Measurement Uncertainty

In acute inflammation, bacterial infections, tissue necrosis and trauma, CRP rises above 10 and may exceed 100 mg/L.


This test reports sufficiently low values to be used in cardiac risk stratification and is considered an hsCRP test. According to Canadian Cardiovascular Society guidelines, pharmacological therapy may be indicated in adults with moderate risk for CAD if hsCRP >2mg/L.

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