C-Reactive Protein High Sensitivity
Ordering Info & Methodology
Test Code
Cerner Synonyms
CRPB
CRP High Sensitivity, C Reactive Protein, C Reactive Protein (CRP), CRP (C-Reactive Protein), CRP, C-Reactive, hsCRP
Turn Around Time
Methodology
Analyzed within 4 hours of receipt, 24/7. Available on a STAT basis.
Immunoturbidimetric, Roche cobas c
Ordering Guide
If ordered together with ESR, only CRP will be performed.
Specimen Requirements
Sample Type
Collection Container
Alternate Collection Containers
Lithium Heparin Plasma
Light Green
Gold, Red
1.0 mL
Seven days
Add on stability
This is the length of time after sample collection that this analyte is stable. Test can be added to a previously collected sample if the time since collection is less than the add on stability time.
Minimum Volume
Add On Stability
Collection and Shipping Requirements
Refrigerate. Send on ice pack within 3 days of collection or frozen if longer.
Reference Intervals
Female Reference Interval
Age Category | Reference Interval | units |
|---|---|---|
0 y - <2 d | Not Established | mg/L |
< 15 d | < 6.1 | mg/L |
15 d - <19 y | < 2.1 | mg/L |
≥ 20 y | < 3.1 | mg/L |
Male Reference Interval
Age Category | Reference Interval | units |
|---|---|---|
0 y - <2 d | Not Established | mg/L |
< 15 d | < 6.1 | mg/L |
15 d - <19 y | < 2.1 | mg/L |
≥ 20 y | < 3.1 | mg/L |
Additional Notes
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Measurement Uncertainty (MU)
Every laboratory value is an estimate of the true concentration of substance. MU is the 95% confidence interval around that estimate. 95% of the time, the true concentration will be within the range of the reported value ±MU. This value is based on analytical variability (precision) and does not reflect other factors such as sample collection and handling which may also affect the result.
Example
Reported sodium = 140 mmol/L
Sodium MU = 1%
Expanded uncertainty = 140 mmol/L ± 1% or 140mmol/L ± 1.4 mmol/L
Interpretation - the true value of sodium in the sample is in the range 138.6-141.4 mmol/L, with 95% confidence.
4%
Measurement Uncertainty
In acute inflammation, bacterial infections, tissue necrosis and trauma, CRP rises above 10 and may exceed 100 mg/L.
This test reports sufficiently low values to be used in cardiac risk stratification and is considered an hsCRP test. According to Canadian Cardiovascular Society guidelines, pharmacological therapy may be indicated in adults with moderate risk for CAD if hsCRP >2mg/L.