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Hemoglobin A1C

Ordering Info & Methodology

Test Code

Cerner Synonyms


Hgb A1c, HbA1c, A1c, Hemoglobin A1c, Glycosylated Hemoglobin, Glycated Hb, HbA1C, A1C

Turn Around Time


Analyzed within 1 day of receipt when received Monday-Friday.

Electrochemiluminescent immunoassay (Roche CobasPro®)

Ordering Guide

Interpret results with caution when analyzing hemoglobin variants due to analytical (CC, SS, SC, persistence of hemoglobin F) and pathophysiological effects (variants which effect hemoglobin half-life) on test results which may interfere with the relationship between glycemic status and HbA1c.

Specimen Requirements

Sample Type

Collection Container

Alternate Collection Containers

Whole Blood EDTA


3.0 mL

Seven days

Add on stability
This is the length of time after sample collection that this analyte is stable. Test can be added to a previously collected sample if the time since collection is less than the add on stability time.

Minimum Volume

Add On Stability

Collection and Shipping Requirements

Do not spin or separate. Refrigerate. Send on ice pack.

Reference Intervals

Female Reference Interval

Age Category
Reference Interval
≥ 0 y

Male Reference Interval

Age Category
Reference Interval
≥ 0 y
Additional Notes

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Measurement Uncertainty (MU)
Every laboratory value is an estimate of the true concentration of substance. MU is the 95% confidence interval around that estimate. 95% of the time, the true concentration will be within the range of the reported value ±MU. This value is based on analytical variability (precision) and does not reflect other factors such as sample collection and handling which may also affect the result.


Reported sodium = 140 mmol/L
Sodium MU = 1%
Expanded uncertainty = 140 mmol/L ± 1% or 140mmol/L ± 1.4 mmol/L
Interpretation - the true value of sodium in the sample is in the range 138.6-141.4 mmol/L, with 95% confidence.


Measurement Uncertainty

HbA1c will be decreased in patients with hemolytic anemia and can be extremely low in some patients on antiretroviral therapy. HbA1c is also misleading in patients with polycythemia, recent blood loss or transfusion, and dialysis patients. HbA1c is not designed to diagnose or manage diabetes in pregnancy.

Diagnosis of diabetes (CDA Guidelines) - HbA1C ≥ 6.5%

Treatment targets should be individualized for a patient's age, comorbidities, and hypoglycemia risk. See guideline tool.


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