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Estradiol

Ordering Info & Methodology

Test Code

Cerner Synonyms

E2

Estrogen Level, Estradiol, Enhanced Estradiol, Extracted Estradiol

Turn Around Time

Methodology

Analyzed within 4 days of receipt.

Competitive immunoassay, electrochemiluminescence, Roche Cobas

Ordering Guide

Specimen Requirements

Sample Type

Collection Container

Alternate Collection Containers

Serum

Red

0.5 mL

Two days

Add on stability
This is the length of time after sample collection that this analyte is stable. Test can be added to a previously collected sample if the time since collection is less than the add on stability time.

Minimum Volume

Add On Stability

Collection and Shipping Requirements

Freeze. Send on ice pack.

Reference Intervals

Female Reference Interval

Age Category
Reference Interval
units
0 y - <12 m
<133
pmol/L
12 m - <5 y
<90
pmol/L
5 y - <10 y
<150
pmol/L
10 y - Menarche
<855
pmol/L
Menarche - Menopause
See Comment(s)
pmol/L
Post Menopause
<90
pmol/L

Male Reference Interval

Age Category
Reference Interval
units
0 y - <12 m
<90
pmol/L
12 m - <5 y
<90
pmol/L
5 y - <10 y
<90
pmol/L
10 y - <14 y
<125
pmol/L
14 y - <19 y
<150
pmol/L
≥ 19 y
95-220
pmol/L
Additional Notes

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Measurement Uncertainty (MU)
Every laboratory value is an estimate of the true concentration of substance. MU is the 95% confidence interval around that estimate. 95% of the time, the true concentration will be within the range of the reported value ±MU. This value is based on analytical variability (precision) and does not reflect other factors such as sample collection and handling which may also affect the result.

Example

Reported sodium = 140 mmol/L
Sodium MU = 1%
Expanded uncertainty = 140 mmol/L ± 1% or 140mmol/L ± 1.4 mmol/L
Interpretation - the true value of sodium in the sample is in the range 138.6-141.4 mmol/L, with 95% confidence.

6%

Measurement Uncertainty

Information on assay interferences

Substance

Interferent?

Details

Biotin

Yes

Interference possible in patients taking high dose (>5mg/day) biotin supplementation

Abemaciclib

No

No known test interference on the Roche method used at St Paul’s Hospital. This has been documented by the St. Paul's Hospital laboratory in a small number of cases where there was detectable interference on the Abbott Alinity method (this method is not used by Providence Health Care facilities but is used elsewhere in BC).


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